Back Messi at 4/1 or Aguero at 10/1 to Score First

Barcelona may have failed to kill off the tie as Leo Messi missed a last-gasp penalty at the Etihad, but they remain hot favourites to go through after the 2-1 win in England, especially given the impressive run of 16 wins in 17 games.

Manchester City are in a very difficult position after the shocking loss to Burnley at the weekend, but the Citizens might be able to keep the tie alive if they can score an early goal at Camp Nou and put pressure on the opposition.

And with both Leo Messi and Sergio Aguero scoring goals for fun this season, chances are one of them will open the scoring, so bear in mind that Ladbrokes has enhanced the price on Messi or Aguero to score the first goal to 4/1 and 10/1 respectively.